合成化学任课教师（柴卓副教授）
教育经历
1999年9月–2003年7月 安徽师范大学 化学专业 理学学士
2003年9月–2008年7月 中国科学院上海有机化学研究所 有机化学专业 理学博士
工作经历
2008年–2009年 中国科学院上海有机化学研究所 助理研究员
2009年–2011年 Montana State University （USA） 博士后
2011年–2012年 Université de Rouen et INSA de Rouen (France) 博士后
主持项目
5. “钯(II)-Br?nsted acid-亚磷酸酰胺体系在氧化性反应条件下的不对称协同催化应用研究”，国家自然科学基金面上项目（21472001），84万元，2015年1月-2018年12月。
4. “烯烃化合物的不对称串联亲电加成–成环反应研究”，国家自然科学基金青年基金项目（21202001），25万元，2013年1月-2015年12月，已结题。
3. “基于不对称亲电反应的毒扁豆碱类生物碱的合成研究”，安徽省自然科学基金面上项目（1308085MB17），5万元，2013年7月-2015年6月，已结题。
2. “基于不对称亲电反应的吡咯并吲哚啉类生物碱的合成研究”，中科院天然产物重点实验室开放基金项目，3万元，2012年12月至2014年12月，已结题。
1. 安徽师范大学博士科研启动基金，2万元，项目负责人。
研究领域
1. 不对称催化
2. 有机合成
3. 金属有机化学
讲授课程
1. 《精细有机合成》，《合成化学》
2. 基础/综合化学实验
2012年以来代表论文
20. Deju Hua, Pengfei Yang, Yue Shen, Gaosheng Yang*, Zhuo Chai*, “PCl5-mediated ring-openings of trans-2,3-disubstituted cyclopropane-1,1-diesters: a stereoselective way to trisubstituted vinyl cholorides”, Tetrahedron 2017, 73, 1205–1210.
19. Zhuo Chai, Jiang Chu, Yunyi Qi, Mujun Tang, Jinsong Hou and Gaosheng Yang*, “Half-sandwich chiral rare-earth metal complexes with linked tridentate amido-indenyl ligand: synthesis, characterization, and catalytic properties for intramolecular hydroamination”, RSC Adv., 2017, 7, 1759–1765.
18. Zhuo Chai,* Pei-Jun Yang, Hu Zhang, Shaowu Wang, Gaosheng Yang, “Synthesis of Chiral Vicinal Diamines by Silver(I)-Catalyzed Enantioselective Aminolysis of N-Tosylaziridines”, Angew. Chem. Int. Ed. 2017, 56, 650–654.
17. Zhuo Chai,* Jia-Nan Chen, Zhen Liu, Xue-Fei Li, Pei-Jun Yang, Ji-Ping Hu, Gaosheng Yang, “[3+2]-Annulations of N-alkyl-3-substituted indoles with quinone monoketals catalysed by Br?nsted acids”, Org. Biomol. Chem. 2016, 14, 1024–1030.
16. Zhuo Chai,* You-Min Zhu, Pei-Jun Yang, Shaoyin Wang, Shaowu Wang,* Zhen Liu, Gaosheng Yang, “Copper(I)-Catalyzed Kinetic Resolution of N-Sulfonylaziridines with Indoles: Efficient Construction of Pyrroloindolines”, J. Am. Chem. Soc. 2015, 137, 10088–10091.
15. Gaosheng Yang,* Tingting Wang, Jun Chai, Zhuo Chai,* “AlCl3-Catalyzed [3+2] Annulations of cis-2,3-Disubstituted Cyclopropane 1,1-Diesters with Cyclic Ketones: Diastereoselective Construction of Spirotetrahydrofurans”, Eur. J. Org. Chem. 2015, 1040–1046.
14. Zhuo Chai, Dezhi Hua, Kui Li, Jiang Chu, Gaosheng Yang,* “A novel chiral yttrium complex with a tridentate linked amido-indenyl ligand for intramolecular hydroamination”, Chem. Commun. 2014, 50, 177–179.
13. Zhuo Chai,* Biao Wang, Jia-Nan Chen, Gaosheng Yang, “Arylation of Azlactones using Diaryliodonium Bromides and Silver Carbonate: Facile Access to alpha-Tetrasubstituted Amino Acid Derivatives”, Adv. Synth. Catal. 2014, 356, 2714–2718.
12. Zhuo Chai, Dezhi Hua, Kui Li, Jiang Chu, Gaosheng Yang,* “Rare-earth metal complexes with tridentate linked amido-indenyl ligand: Synthesis, characterization, and catalytic properties for intramolecular hydroamination”, J. Organomet. Chem. 2014, 768, 136–139.
11. Shaoyin Wang, Xiancui Zhu, Zhuo Chai,* and Shaowu Wang,* “Synthesis of polysubstituted pyrroles via [3+2]-annulation of aziridines and beta-nitroalkenes under aerobic conditions”, Org. Biomol. Chem. 2014, 12, 1351–1356.
10. Yongxian Sun, Gaosheng Yang,* Zhuo Chai,* Xiaolong Mu, Jun Chai, “AlCl3-promoted [3+2] annulation of cis-2,3-disubstituted cyclopropane 1,1-diesters with isothiocyanates: stereoselective synthesis of densely substituted 2-iminodihydrothiophenes”, Org. Biomol. Chem. 2013, 11, 7859–7868.
9. Yongxian Sun, Gaosheng Yang,* Yue Shen, Hua Zan, Zhuo Chai,* “Stereoselective cyclopropanation of a-bromochalcone with diethyl malonate promoted by K2CO3”,Tetrahedron 2013, 69, 5104–5111.
8. Gaosheng Yang,* Yongxian Sun, Yue Shen, Zhuo Chai,* Shuangliu Zhou, Jiang Chu, Jun Chai, “cis-2,3-Disubstituted Cyclopropane 1,1-Diesters in [3+2] Annulations with Aldehydes: Highly Diastereoselective Construction of Densely Substituted Tetrahydrofurans”, J. Org. Chem. 2013, 78, 5393–5400.
博士和博士后期间代表论文
7. Zhuo Chai, Jean-Philippe Bouillon, Dominique Cahard,* “Chiral Br?nsted Acid-Catalyzed Diastereo- and Enantioselective Synthesis of CF3-Substituted Aziridines”,Chem. Commun. 2012, 48, 9471–9473.
6. Zhuo Chai, Trevor J. Rainey,* “Pd(II)/Br?nsted Acid Catalyzed Enantioselective Allylic C-H Activation for the Synthesis of Spirocyclic Rings”, J. Am. Chem. Soc. 2012,134, 3615–3618.
5. Zhuo Chai, Gang Zhao,* “Efficient Organocatalysts Derived From Simple Chiral Acyclic Amino Acids in Asymmetric Synthesis” Catal. Sci. Technol. 2012, 2, 29–41.
4. Zhuo Chai, Hai-Feng Wang, Gang Zhao,* “Ni-Catalyzed Carbocyclization of 1,6-Enynes Mediated by Dialkylzinc Reagents: Me2Zn or Et2Zn Makes a Difference”,Synlett 2009, 1785–1790.
3. Zhuo Chai, Zheng-Feng Xie, Xin-Yuan Liu, Ji-De Wang*, Gang Zhao*, “Tandem Addition/Cyclization Reaction of Organozinc Reagents to 2-Alkynyl Aldehydes: Highly Efficient Regio- and Enantioselective Synthesis of 1,3-Dihydroisobenzofurans and Tetrasubstituted Furans”, J. Org. Chem. 2008, 73, 2947–2950.
2. Zhuo Chai, Xin-Yuan Liu, Jun-Kang Zhang, Gang Zhao*, “Enantioselective Addition of Alkenylzinc Reagents to Aldehydes With Organoboronates as the Alkenyl Source”, Tetrahedron: Asymmetry 2007, 18, 724–728.
1. Zhuo Chai, Xin-Yuan Liu, Xiao-Yu Wu, Gang Zhao*, “Synthesis of Modular Thiophene-Oxazoline Ligands and Their Application in the Asymmetric Phenyl Transfer Reaction to Aldehydes”, Tetrahedron: Asymmetry 2006, 17, 2442–2447.
会议论文及报告
1. 第十三届江淮有机化学论坛，青年学者报告，“Copper(I)-Catalyzed Enantioselective [3+2] Annulation of Indoles and N-Sulfonylaziridines”，会议时间：2015年10月30日至11月1日，南京大学（江苏南京）。
专 利
1. 柴卓，杨高升，李奎，华德智，“一种稀土配合物催化剂，其制备方法、用途以及应用方法”，中国发明专利, 专利号：ZL 2013 1 0394971.4.
2. 柴卓，朱佑民，王绍武，杨培俊，杨高升，“一种手性六氢吡咯并吲哚类化合物的制备方法”，中国发明专利, 申请号：CN201510262771.2.
3. 柴卓，杨培俊，王绍武，杨高升，“一种手性邻二胺类化合物及其制备方法”，中国发明专利, 申请号：CN201610234895.4.
论 著
1. Gang Zhao*, Zhuo Chai, Chapter 3: Insoluble Resin-supported Catalysts in Recoverable and Recyclable Catalysts, Benaglia, M. Eds.; John Wiely & Sons: Chichester, 2009, Chapter 3, pp 49-72.